The two clubs are in the midst of very different seasons, the Saints lodged in the relegation zone after another disappointing defeat on the weekend – although the cup has provided some respite including the quarter-final victory over Manchester City.
Sat in the Champions League places, Newcastle have not reached the final of this competition since 1976 as they look to end a decades-long wait for a major trophy.
Date, kick-off time and venue
Southampton vs Newcastle is scheduled for an 8pm GMT kick-off time tonight, Tuesday, January 24, 2023.
The match will take place at St Mary’s Stadium.
Where to watch Southampton vs Newcastle
TV channel: In the UK, the match will be televised live on Sky Sports Main Event and Football, with coverage starting at 7pm this evening.
Live stream: Fans can also catch the game live online via the Sky go app.
Southampton vs Newcastle team news
Southampton vs Newcastle prediction
The Magpies are on a relentless march this season and could put one foot in the final with a convincing display.
Newcastle to win, 1-0.
Head to head (h2h) history and results
Saints have won one of their last 11 meetings.
Southampton wins: 38
Newcastle wins: 43
Southampton vs Newcastle match odds
Odds via Betfair (subject to change).
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